GSK-3β inhibitor 12
CAS No. 784170-07-6
GSK-3β inhibitor 12( —— )
Catalog No. M35424 CAS No. 784170-07-6
GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 103 | In Stock |
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| 5MG | 155 | In Stock |
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| 10MG | 250 | In Stock |
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| 25MG | 419 | In Stock |
|
| 50MG | 596 | In Stock |
|
| 100MG | 803 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK-3β inhibitor 12
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NoteResearch use only, not for human use.
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Brief DescriptionGSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.
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DescriptionGSK-3β inhibitor 12 (compound 15) is an inhibitor of GSK-3β. GSK-3β inhibitor 12 inhibits 49.11% and 37.11% activity of 25 μM and 50 μM GSK-3β, respectively. GSK-3β inhibitor 12 can be used for the research of neurodegenerative diseases.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetGSK-3
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RecptorGSK-3
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Research Area——
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Indication——
Chemical Information
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CAS Number784170-07-6
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Formula Weight271.34
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Molecular FormulaC14H13N3OS
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1=CN=C(NC(=O)CC2=CNC3=CC=CC=C23)S1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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9-ING-41
9-ING-41 is a glycogen synthase kinase-3 inhibitor.9-ING-41 (2, 4 μM; 48 hours) decreases neuroblastoma cell viability induces apoptosis[2]. 9-ING-41 (0.1-1 μM) inhibits GSK-3 leading to a decreased expression of the NF-κB target XIAP and significant apoptosis in neuroblastoma cells as shown by PARP cleavage, an apoptosis marker[1]. 9-ING-41 (0.5, 1.0, 1.5, 2.0 μM) inhibits the proliferation rate of all TCL and MCL lines with concentrations as low as 1.0 mM.
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CHIR-99021 trihydroc...
A potent, specific GSK-3 inhibitor with IC50 of 5 nM and 10 nM for GSK3β and GSK3α, respectively.
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ABC 1183
ABC1183 is a potent, selective, orally active GSK3α/β and CDK9 inhibitor with IC50 of 327/657 nM and 321 nM (CDK9/cyclin T1).
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